The Personal Discovery Process provides individuals with treatment-driven research on an unprecedented scale. Our Personal Discovery Process (PDP) is effectively a massive clinical trial for a single patient. We engineer the genetic complexity of each patient's unique tumour network into an army of 400,000 fruit fly "avatars". Using robotics, we evaluate up to 1,800 FDA approved drugs including non-cancer drugs, to identify drug combinations that are efficacious in the individual's avatar population.
The Icahn School of Medicine at Mount Sinai developed the PDP methodology over years of clinical research, with technical input from the FDA. They found that real-world patient tumours are made resistant to single drug treatments by mutations in several genes, including genes not previously associated with cancer. Such resistant tumours can, however, be effectively addressed with novel combinations of FDA approved drugs. The most effective combinations almost always include non-cancer drugs. The PDP methods are licensed exclusively to My Personal Therapeutics.
DEVELOPMENT OF PERSONALISED TREATMENT RECOMMENDATIONS FOR COLORECTAL CANCER PATIENTS
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